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KMID : 1134820150440081157
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Journal of the Korean Society of Food Science and Nutrition
2015 Volume.44 No. 8 p.1157 ~ p.1164
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Comparison of Antioxidant Activities of Water Extract from Dandelion (Taraxacum officinale) Aerial Parts, Roots, and Their Mixtures
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Jung Hyun-Jung
Sung Hea-Mi
Kim Kyoung-Mi
Shin Yu-Rim
Wee Ji-Hyang
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Abstract
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The present investigation evaluated the antioxidant activities of water extracts from dandelion (Taraxacum officinale) aerial parts, roots, and mixed extracts. Mixed extract of T. officinale was a mixture of aerial parts and roots at 9:1 and 8:2 weight ratios. Extracts from aerial parts (DAE), roots (DRE), and mixture of aerial parts and roots (DME) were measured for cell viability and catalase activity in HepG2 cells, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, and lipid peroxidation inhibitory activity. Cell viabilities of HepG2 cells treated with DAE, DRE, DME 8:2, and DME 9:1 against H2O2-induced oxidative damage were 63.4%, 54.6%, 76.7% and 83.4% at a concentration of 400 μg/mL, respectively. Catalase activity was highest in DME 9:1 (12.2 mU/min/mg protein) compared with DAE (9.0 mU/min/mg protein) and DRE (9.7 mU/min/mg protein). DPPH radical scavenging activity of DME showed a significantly lower EC50 value than DAE (EC50 value of DME 9:1=163.3 μg/mL, DME 8:2=172.4 μg/mL, and DAE=173.7 μg/mL). Lipid peroxidation inhibitory activity of DME showed a significantly lower EC50 value than DAE [EC50 values of DME (9:1)=454.4 μg/mL, DME (8:2)=426.6 μg/mL, and DAE=654.7 μg/mL]. The results indicate that a small amount of T. officinale roots increased antioxidant activity of aerial parts. Especially, a 9:1 mixture was more valuable than 8:2 mixture for industry.
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KEYWORD
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dandelion, Taraxacum officinale, antioxidant activity, luteolin, chicoric acid
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